James Reilly Keffer, D.O.
Physical Medicine & Rehabilitation
James Reilly Keffer is a Physical Medicine & Rehabilitation specialist based in Charleston, SC with over 27 years of clinical experience. Medicare-enrolled per CMS records and offers virtual telehealth visits.
Also practices: PAIN MANAGEMENT
James Reilly Keffer, D.O. practices as part of a group physical medicine & rehabilitation specialist practice in Charleston, SC. He has been practicing since 2006 — over 27 years. CMS Medicare data shows his patients commonly have hypertension, high cholesterol, and arthritis.
At a glance
- Uses generic medications more than 95% of reporting doctors in South Carolina
- Virtual visits available — no app or travel required
Older · 291dNPPES updated 2025-08-05 · verify NPI on CMS · Verify license at South Carolina Board of Medical Examiners
Contact & Location
Practice Location
2145 Henry Tecklenburg Dr Ste 220, Charleston, SC 29414-5893
How Does This Doctor Compare?
Based on Medicare data, this doctor favors affordable generic drugs over brand-name ones.
Opioid Rx
↓ Lower = better50.22%
South Carolina avg: 4.6 · US avg: 5.1
⚠ Lower than most doctors nationally(+45.1 pts)
50.22% of this doctor's prescriptions are opioid pain medications. Lower means more cautious prescribing.
Generic Rx
↑ Higher = better97.7%
South Carolina avg: 83.3 · US avg: 82.8
✓ Higher than most doctors nationally(+14.9 pts)
Top 5% of reporting doctors in South CarolinaHow often this doctor prescribes affordable generic drugs instead of expensive brand-name ones.
Medicare Patients
256
Unique beneficiaries
Standard volumePrescription Recipients
218
Patients prescribed
Prescriptions Written
930
Total claims
Total Medicare drug cost: $36k
Percentile rankings compared against 605 reporting peers in South Carolina.
Data Note: Sourced from CMS Medicare Provider Utilization & Payment Data. Percentile rankings compare this provider against all peers with reported data in the same state. Updated annually to reflect the latest federal reporting cycle.
What This Doctor Treats Most
Based on Medicare claims data — here's what patients commonly see this doctor for
Based on Medicare data, this doctor primarily manages Hypertension, High Cholesterol, and Arthritis.
High blood pressure — a leading risk factor for heart disease and stroke
US avg: 70.2%↑ More patients than average (+5%) — a focus area for this doctor
Elevated cholesterol or triglycerides that increase heart disease risk
US avg: 70.4%↑ More patients than average (+5%) — a focus area for this doctor
Joint inflammation causing pain, swelling, and stiffness
US avg: 49.3%↑ More patients than average (+26%) — a focus area for this doctor
A condition where the body cannot properly regulate blood sugar levels
US avg: 34.5%↑ More patients than average (+2%) — a focus area for this doctor
Excessive worry or fear that interferes with daily life
US avg: 34.1%↓ Fewer patients than average (-4%) — less common here
Conditions affecting emotional state, including depression and bipolar disorder
Reduced blood flow to the heart muscle, commonly known as coronary artery disease
US avg: 31.7%↓ Fewer patients than average (-5%) — less common here
A mood disorder causing persistent sadness and loss of interest in activities
US avg: 31.8%↓ Fewer patients than average (-6%) — less common here
Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.
$135 received from industry
7 transactions reported in 2024 ·Low tier
Payments include consulting fees, speaking honoraria, food & beverage, travel, research support, and ownership interests from drug and medical device manufacturers. Disclosure is required by the federal Physician Payments Sunshine Act. These payments do not necessarily indicate conflicts of interest. National median: $338 across 136 000 tracked providers.
Tiers — Low: under $500 · Moderate: $500-5 000 · High: $5 000-25 000 · Very High: $25 000+. Source: CMS Open Payments 2024, attributed to James Reilly Keffer's NPI.
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Background & Specialty
Education, training, and specialty classification from CMS NPPES and Medicare records.
Board certified · Aug 4, 2025
Self-reported via NPPES
27 years in practice
Experienced
Physical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and treating patients with physical disabilities. These disabilities may arise from conditions affecting the musculoskeletal system such as neck and back pain, sports injuries, or other painful conditions affecting the limbs, such as carpal tunnel syndrome. Alternatively, the disabilities may result from neurological trauma or disease such as spinal cord injury, head injury or stroke. A physician certified in physical medicine and rehabilitation is often called a physiatrist. The primary goal of the physiatrist is to achieve maximal restoration of physical, psychological, social and vocational function through comprehensive rehabilitation. Pain management is often an important part of the role of the physiatrist. For diagnosis and evaluation, a physiatrist may include the techniques of electromyography to supplement the standard history, physical, x-ray and laboratory examinations. The physiatrist has expertise in the appropriate use of therapeutic exercise, prosthetics (artificial limbs), orthotics and mechanical and electrical devices.
Taxonomy: 208100000X
Mailing address
Po Box 751649, Charlotte, NC 28275-1649
Differs from practice location
Virtual Physical Medicine & Rehabilitation Care With James Reilly Keffer
NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.
Schedule a virtual visit with James Reilly Keffer for blood pressure monitoring, cholesterol management, arthritis follow-ups — no travel to Charleston required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes. Medicare enrolled per CMS records.
Frequently Asked Questions
Common questions about James Reilly Keffer
NPI records show Dr. Keffer as active with telehealth listed in Charleston, SC. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (843) 723-8823.
Sourced from CMS NPPES · OIG LEIE · CMS Medicare Part D · CMS Open Payments 2024 · CMS Physician Comparator. See Data Methodology.
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Contact James Reilly Keffer
Practice Location
2145 Henry Tecklenburg Dr Ste 220, Charleston, SC 29414-5893
Mailing Address
Po Box 751649, Charlotte, NC 28275-1649
This is a provider directory. Contact the office directly to schedule appointments.
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