Jennifer L. Hsu, M.D.

Infectious Disease Internal Medicine

Internal Medicine

Jennifer L. Hsu is an Infectious Disease Internal Medicine specialist based in Sioux Falls, SD with over 21 years of clinical experience. Medicare-enrolled per CMS records and offers virtual telehealth visits.

Also practices: INTERNAL MEDICINE

(605) 328-8120Sioux Falls, SD
Telehealth Available
NPI Active per CMS — Q2 2026|Medicare Enrolled|Order & Refer

Jennifer L. Hsu, M.D. has practiced internal medicine for 21+ years, working in group practice. She graduated from University of Missouri, Columbia School of Medicine in 2005 and has 21+ years of clinical experience. Among her Medicare patients, common conditions include hypertension, high cholesterol, and arthritis (per CMS data).

At a glance

  • Uses generic medications more than 38% of reporting doctors in South Dakota
  • Virtual visits available — no app or travel required
1 of 15 Internal Medicine providers in SDSee all Internal Medicine in Sioux Falls21+ years experienceNPI since 2006

Older · 1517dNPPES updated 2022-03-29 · verify NPI on CMS · Verify license at South Dakota Board of Medical & Osteopathic Examiners

Contact & Location

Practice Location

1205 S Grange Ave Ste 401, Sioux Falls, SD 57105-0410

CMS Clinical Data

How Does This Doctor Compare?

Based on Medicare data, this doctor favors affordable generic drugs over brand-name ones.

Generic Rx

↑ Higher = better

84.6%

South Dakota avg: 80.6 · US avg: 82.8

Higher than most doctors nationally(+1.8 pts)

How often this doctor prescribes affordable generic drugs instead of expensive brand-name ones.

Medicare Patients

322

Unique beneficiaries

Standard volume

Prescription Recipients

84

Patients prescribed

Prescriptions Written

344

Total claims

Total Medicare drug cost: $149k

Percentile rankings compared against 117 reporting peers in South Dakota.

Data Note: Sourced from CMS Medicare Provider Utilization & Payment Data. Percentile rankings compare this provider against all peers with reported data in the same state. Updated annually to reflect the latest federal reporting cycle.

Patient Condition Panel

What This Doctor Treats Most

Based on Medicare claims data — here's what patients commonly see this doctor for

Based on Medicare data, this doctor primarily manages Hypertension, High Cholesterol, and Arthritis.

Hypertension
Higher than avg (+5%)75%

High blood pressure — a leading risk factor for heart disease and stroke

US avg: 70.2%

↑ More patients than average (+5%) — a focus area for this doctor

High Cholesterol
Higher than avg (+4%)74%

Elevated cholesterol or triglycerides that increase heart disease risk

US avg: 70.4%

↑ More patients than average (+4%) — a focus area for this doctor

Arthritis
Higher than avg (+9%)58%

Joint inflammation causing pain, swelling, and stiffness

US avg: 49.3%

↑ More patients than average (+9%) — a focus area for this doctor

Diabetes
Higher than avg (+17%)51%

A condition where the body cannot properly regulate blood sugar levels

US avg: 34.5%

↑ More patients than average (+17%) — a focus area for this doctor

Chronic Kidney Disease
Higher than avg (+18%)48%

Gradual loss of kidney function over time, often linked to diabetes or hypertension

US avg: 29.6%

↑ More patients than average (+18%) — a focus area for this doctor

Ischemic Heart Disease
Higher than avg (+14%)46%

Reduced blood flow to the heart muscle, commonly known as coronary artery disease

US avg: 31.7%

↑ More patients than average (+14%) — a focus area for this doctor

Heart Failure
Higher than avg (+24%)46%

The heart cannot pump blood efficiently enough to meet the body's needs

US avg: 22.5%

↑ More patients than average (+24%) — a focus area for this doctor

Mood Disorders
45%

Conditions affecting emotional state, including depression and bipolar disorder

GeneralBehavioralNational avg

Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.

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Background & Specialty

Education, training, and specialty classification from CMS NPPES and Medicare records.

Career Journey
  1. Graduated medical school · 2005

    University of Missouri, Columbia School of Medicine

  2. Board certified · Mar 28, 2022

    Self-reported via NPPES

  3. 21 years in practice

    Experienced

Internal MedicineInfectious Disease in Sioux FallsAllopathic & Osteopathic Physicians

Infectious disease specialists diagnose and treat complex infections including HIV/AIDS, hepatitis, tuberculosis, antibiotic-resistant infections (MRSA), post-surgical infections, and travel-related illnesses. They also provide pre-travel vaccination counseling and manage infections in immunocompromised patients.

Taxonomy: 207RI0200X

Education & Training

University of Missouri, Columbia School of Medicine (Class of 2005)

Practice Footprint

Mailing address

Po Box 5074, Sioux Falls, SD 57117-5074

Differs from practice location

Virtual Infectious Disease Care With Jennifer L. Hsu

NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.

Schedule a virtual visit with Jennifer L. Hsu for blood pressure monitoring, cholesterol management, arthritis follow-ups — no travel to Sioux Falls required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes. Medicare enrolled per CMS records.

Frequently Asked Questions

Common questions about Jennifer L. Hsu

Dr. Hsu is listed as active in the NPI registry with telehealth listed in Sioux Falls, SD. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (605) 328-8120.

Verified across 4 federal data sources

Sourced from CMS NPPES · OIG LEIE · CMS Medicare Part D · CMS Physician Comparator. See Data Methodology.

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Medical Disclaimer: NPI Telehealth is a provider directory for informational purposes only. This page does not constitute medical advice, diagnosis, or treatment recommendations. Provider data is sourced from the CMS NPPES federal registry and public Medicare datasets. NPI Telehealth does not verify clinical qualifications beyond federal records. Data may not reflect real-time availability — always contact the provider's office directly to confirm details before seeking care.

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