Mark Edwin Zafereo, MD

Otolaryngology

Mark Edwin Zafereo is an Otolaryngology specialist based in Houston, TX with over 21 years of clinical experience. Offers virtual telehealth visits.

(713) 792-6525Houston, TX
Telehealth Available
NPI Active per CMS — Q2 2026

Mark Edwin Zafereo, MD has been part of the Houston medical community since 2008 in independent practice. A University of Texas Medical School at Houston graduate since 2005, he brings 21+ years of experience. CMS Medicare data shows his patients commonly have hypertension, high cholesterol, and arthritis.

1 of 64 Otolaryngology providers in TXSee all Otolaryngology in Houston21+ years experienceNPI since 2008

Older · 5235dNPPES updated 2012-01-23 · verify NPI on CMS · Verify license at Texas Medical Board

Contact & Location

Practice Location

1515 Holcombe Blvd Unit 1445 Md Anderson Cancer Center Dept Head and Neck Surgery, Houston, TX 77030-4000

Patient Condition Panel

What This Doctor Treats Most

Based on Medicare claims data — here's what patients commonly see this doctor for

Based on Medicare data, this doctor primarily manages Hypertension, High Cholesterol, and Arthritis.

Hypertension
75%

High blood pressure — a leading risk factor for heart disease and stroke

High Cholesterol
75%

Elevated cholesterol or triglycerides that increase heart disease risk

Arthritis
50%

Joint inflammation causing pain, swelling, and stiffness

Diabetes
32%

A condition where the body cannot properly regulate blood sugar levels

Ischemic Heart Disease
26%

Reduced blood flow to the heart muscle, commonly known as coronary artery disease

Anxiety Disorders
25%

Excessive worry or fear that interferes with daily life

Mood Disorders
25%

Conditions affecting emotional state, including depression and bipolar disorder

Cancer
22%

Diseases involving abnormal cell growth with potential to spread to other body parts

GeneralBehavioralNational avg

Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.

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Background & Specialty

Education, training, and specialty classification from CMS NPPES and Medicare records.

Career Journey
  1. Graduated medical school · 2005

    University of Texas Medical School at Houston

  2. 21 years in practice

    Experienced

OtolaryngologyAllopathic & Osteopathic Physicians

An otolaryngologist-head and neck surgeon provides comprehensive medical and surgical care for patients with diseases and disorders that affect the ears, nose, throat, the respiratory and upper alimentary systems and related structures of the head and neck. An otolaryngologist diagnoses and provides medical and/or surgical therapy or prevention of diseases, allergies, neoplasms, deformities, disorders and/or injuries of the ears, nose, sinuses, throat, respiratory and upper alimentary systems, face, jaws and the other head and neck systems. Head and neck oncology, facial plastic and reconstructive surgery and the treatment of disorders of hearing and voice are fundamental areas of expertise.

Taxonomy: 207Y00000X

Education & Training

University of Texas Medical School at Houston (Class of 2005)

Practice Footprint

Mailing address

2211 South Blvd, Houston, TX 77098-5224

Differs from practice location

Virtual Otolaryngology Care With Mark Edwin Zafereo

NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.

Schedule a virtual visit with Mark Edwin Zafereo for blood pressure monitoring, cholesterol management, arthritis follow-ups — no travel to Houston required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes.

Frequently Asked Questions

Common questions about Mark Edwin Zafereo

NPI records show Dr. Zafereo as active with telehealth listed in Houston, TX. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (713) 792-6525.

Verified across 3 federal data sources

Sourced from CMS NPPES · OIG LEIE · CMS Physician Comparator. See Data Methodology.

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Medical Disclaimer: NPI Telehealth is a provider directory for informational purposes only. This page does not constitute medical advice, diagnosis, or treatment recommendations. Provider data is sourced from the CMS NPPES federal registry and public Medicare datasets. NPI Telehealth does not verify clinical qualifications beyond federal records. Data may not reflect real-time availability — always contact the provider's office directly to confirm details before seeking care.

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