Mathew Papakyrikos Mazzola, DO
Mathew Papakyrikos Mazzola is an Internal Medicine specialist based in Columbia, SC with over 9 years of clinical experience. Offers virtual telehealth visits.
Mathew Papakyrikos Mazzola, DO specializes in internal medicine, serving patients in Columbia, SC in group practice. He has been in practice for 9+ years. He regularly sees Medicare patients with high cholesterol, hypertension, and arthritis (per CMS claims data).
At a glance
- Uses generic medications more than 48% of reporting doctors in South Carolina
- Virtual visits available — no app or travel required
Older · 2021dNPPES updated 2020-11-09 · verify NPI on CMS · Verify license at South Carolina Board of Medical Examiners
Contact & Location
Practice Location
4540 Trenholm Rd, Columbia, SC 29206-4462
What This Doctor Treats Most
Based on Medicare claims data — here's what patients commonly see this doctor for
Based on Medicare data, this doctor primarily manages High Cholesterol, Hypertension, and Arthritis.
Elevated cholesterol or triglycerides that increase heart disease risk
US avg: 70.4%↑ More patients than average (+5%) — a focus area for this doctor
High blood pressure — a leading risk factor for heart disease and stroke
US avg: 70.2%↓ Fewer patients than average (-1%) — less common here
Joint inflammation causing pain, swelling, and stiffness
US avg: 49.3%↓ Fewer patients than average (-12%) — less common here
A condition where the body cannot properly regulate blood sugar levels
US avg: 34.5%↓ Fewer patients than average (-12%) — less common here
Reduced blood flow to the heart muscle, commonly known as coronary artery disease
US avg: 31.7%↓ Fewer patients than average (-12%) — less common here
Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.
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Background & Specialty
Education, training, and specialty classification from CMS NPPES and Medicare records.
Board certified · Nov 8, 2020
Self-reported via NPPES
9 years in practice
Established
A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and digestive, respiratory and vascular systems. They are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.
Taxonomy: 207R00000X
Mailing address
Po Box 6069, West Columbia, SC 29171-6069
Differs from practice location
Virtual Internal Medicine Care With Mathew Papakyrikos Mazzola
NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.
Schedule a virtual visit with Mathew Papakyrikos Mazzola for cholesterol management, blood pressure monitoring, arthritis follow-ups — no travel to Columbia required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes.
Frequently Asked Questions
Common questions about Mathew Papakyrikos Mazzola
Dr. Mazzola is listed as active in the NPI registry with telehealth listed in Columbia, SC. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (803) 790-4700.
Sourced from CMS NPPES · OIG LEIE · CMS Medicare Part D · CMS Physician Comparator. See Data Methodology.
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Medical Disclaimer: NPI Telehealth is a provider directory for informational purposes only. This page does not constitute medical advice, diagnosis, or treatment recommendations. Provider data is sourced from the CMS NPPES federal registry and public Medicare datasets. NPI Telehealth does not verify clinical qualifications beyond federal records. Data may not reflect real-time availability — always contact the provider's office directly to confirm details before seeking care.
Contact Mathew Papakyrikos Mazzola
Practice Location
4540 Trenholm Rd, Columbia, SC 29206-4462
Mailing Address
Po Box 6069, West Columbia, SC 29171-6069
This is a provider directory. Contact the office directly to schedule appointments.
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