Melissa Ann Destefano, PA-C

Medical Physician Assistant

Melissa Ann Destefano is a Medical Physician Assistant based in Lancaster, PA with over 22 years of clinical experience. Offers virtual telehealth visits.

(717) 396-9167Lancaster, PA
Telehealth Available
NPI Active per CMS — Q2 2026

With over 22 years in medical, Melissa Ann Destefano, PA-C is a long-established medical physician assistant in Lancaster. With 22+ years of experience, she has been practicing in the Lancaster area. Among her Medicare patients, common conditions include high cholesterol, hypertension, and arthritis (per CMS data).

1 of 424 Physician Assistant providers in PASee all Physician Assistant in Lancaster22+ years experienceNPI since 2006

Older · 248dNPPES updated 2025-09-18 · verify NPI on CMS · Verify license at Pennsylvania State Board of Medicine

Contact & Location

Practice Location

2150 Harrisburg Pike Ste 200a, Lancaster, PA 17601-2644

Fax: (717) 396-9064
Patient Condition Panel

What This Doctor Treats Most

Based on Medicare claims data — here's what patients commonly see this doctor for

Based on Medicare data, this doctor primarily manages High Cholesterol, Hypertension, and Arthritis.

High Cholesterol
75%

Elevated cholesterol or triglycerides that increase heart disease risk

Hypertension
70%

High blood pressure — a leading risk factor for heart disease and stroke

Arthritis
65%

Joint inflammation causing pain, swelling, and stiffness

Anxiety Disorders
43%

Excessive worry or fear that interferes with daily life

Mood Disorders
39%

Conditions affecting emotional state, including depression and bipolar disorder

Ischemic Heart Disease
37%

Reduced blood flow to the heart muscle, commonly known as coronary artery disease

Depression
33%

A mood disorder causing persistent sadness and loss of interest in activities

Diabetes
31%

A condition where the body cannot properly regulate blood sugar levels

GeneralBehavioralNational avg

Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.

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Background & Specialty

Education, training, and specialty classification from CMS NPPES and Medicare records.

Career Journey
  1. Board certified · Sep 17, 2025

    Self-reported via NPPES

  2. 22 years in practice

    Experienced

Physician AssistantPhysician Assistants & Advanced Practice Nursing Providers

Definition to come...

Taxonomy: 363AM0700X

Virtual Medical Care With Melissa Ann Destefano

NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.

Schedule a virtual visit with Melissa Ann Destefano for cholesterol management, blood pressure monitoring, arthritis follow-ups — no travel to Lancaster required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes.

Frequently Asked Questions

Common questions about Melissa Ann Destefano

Dr. Destefano is listed as active in the NPI registry with telehealth listed in Lancaster, PA. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (717) 396-9167.

Verified across 3 federal data sources

Sourced from CMS NPPES · OIG LEIE · CMS Physician Comparator. See Data Methodology.

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Medical Disclaimer: NPI Telehealth is a provider directory for informational purposes only. This page does not constitute medical advice, diagnosis, or treatment recommendations. Provider data is sourced from the CMS NPPES federal registry and public Medicare datasets. NPI Telehealth does not verify clinical qualifications beyond federal records. Data may not reflect real-time availability — always contact the provider's office directly to confirm details before seeking care.

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