Melissa M Grube, M.D.

Family Medicine

Melissa M Grube is a Family Medicine specialist based in Mequon, WI with over 9 years of clinical experience. Medicare-enrolled per CMS records and offers virtual telehealth visits.

(262) 243-9600Mequon, WI
Telehealth Available
NPI Active per CMS — Q2 2026|Medicare Enrolled|Order & Refer

Melissa M Grube, M.D. has been part of the Mequon medical community since 2017 in independent practice. A University of Wisconsin School of Medicine graduate since 2017, she brings 9+ years of experience. CMS Medicare data shows her patients commonly have hypertension, high cholesterol, and arthritis. CMS MIPS quality score: 75.75/100 (2023).

At a glance

  • Prescribes opioids less than 51% of reporting doctors in Wisconsin
  • Uses generic medications more than 56% of reporting doctors in Wisconsin
  • Federal MIPS score higher than 4% of MIPS-scored doctors in Wisconsin
  • Virtual visits available — no app or travel required
1 of 436 Family Medicine providers in WISee all Family Medicine in Mequon9+ years experienceNPI since 2017

Older · 2029dNPPES updated 2020-11-02 · verify NPI on CMS · Verify license at Wisconsin Medical Examining Board

Contact & Location

Practice Location

12800 N Port Washington Rd, Mequon, WI 53097-2415

Fax: (262) 243-9661
CMS Clinical Data

How Does This Doctor Compare?

Based on Medicare data, this doctor prescribes opioid pain medications conservatively, favors affordable generic drugs over brand-name ones.

MIPS Score

2023

75.75/100

Wisconsin avg: 82.1 · US avg: 83.6

Lower than most doctors nationally(-7.8 pts)

How the government rates this doctor's Medicare care quality. Scores above 75 are considered good.

Opioid Rx

↓ Lower = better

0.49%

Wisconsin avg: 4.3 · US avg: 5.1

Higher than most doctors nationally(-4.6 pts)

Typical range among reporting doctors in Wisconsin

0.49% of this doctor's prescriptions are opioid pain medications. Lower means more cautious prescribing.

Generic Rx

↑ Higher = better

88.2%

Wisconsin avg: 82.2 · US avg: 82.8

Higher than most doctors nationally(+5.4 pts)

Typical range among reporting doctors in Wisconsin

How often this doctor prescribes affordable generic drugs instead of expensive brand-name ones.

Medicare Patients

165

Unique beneficiaries

Standard volume

Prescription Recipients

425

Patients prescribed

Prescriptions Written

4,854

Total claims

Total Medicare drug cost: $384k

Percentile rankings compared against 779 reporting peers in Wisconsin.

Data Note: Sourced from CMS Medicare Provider Utilization & Payment Data. Percentile rankings compare this provider against all peers with reported data in the same state. Updated annually to reflect the latest federal reporting cycle.

Patient Condition Panel

What This Doctor Treats Most

Based on Medicare claims data — here's what patients commonly see this doctor for

Based on Medicare data, this doctor primarily manages Hypertension, High Cholesterol, and Arthritis.

Hypertension
Lower than avg (-7%)63%

High blood pressure — a leading risk factor for heart disease and stroke

US avg: 70.2%

↓ Fewer patients than average (-7%) — less common here

High Cholesterol
Lower than avg (-15%)55%

Elevated cholesterol or triglycerides that increase heart disease risk

US avg: 70.4%

↓ Fewer patients than average (-15%) — less common here

Arthritis
Lower than avg (-14%)35%

Joint inflammation causing pain, swelling, and stiffness

US avg: 49.3%

↓ Fewer patients than average (-14%) — less common here

Ischemic Heart Disease
Lower than avg (-11%)21%

Reduced blood flow to the heart muscle, commonly known as coronary artery disease

US avg: 31.7%

↓ Fewer patients than average (-11%) — less common here

Mood Disorders
21%

Conditions affecting emotional state, including depression and bipolar disorder

GeneralBehavioralNational avg

Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.

Industry Payment Transparency

$45 received from industry

2 transactions reported in 2024 ·Low tier

View on CMS Open Payments →

Payments include consulting fees, speaking honoraria, food & beverage, travel, research support, and ownership interests from drug and medical device manufacturers. Disclosure is required by the federal Physician Payments Sunshine Act. These payments do not necessarily indicate conflicts of interest. National median: $338 across 136 000 tracked providers.

Tiers — Low: under $500 · Moderate: $500-5 000 · High: $5 000-25 000 · Very High: $25 000+. Source: CMS Open Payments 2024, attributed to Melissa M Grube's NPI.

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Background & Specialty

Education, training, and specialty classification from CMS NPPES and Medicare records.

Career Journey
  1. Graduated medical school · 2017

    University of Wisconsin School of Medicine and Public Health

  2. Board certified · Nov 1, 2020

    Self-reported via NPPES

  3. 9 years in practice

    Established

Family MedicineAllopathic & Osteopathic Physicians

Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadth which integrates the biological, clinical, and behavioral sciences. The scope of family medicine is not limited by age, sex, organ system, or disease entity.

Taxonomy: 207Q00000X

Education & Training

University of Wisconsin School of Medicine (Class of 2017)

Virtual Family Medicine Care With Melissa M Grube

NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.

Schedule a virtual visit with Melissa M Grube for blood pressure monitoring, cholesterol management, arthritis follow-ups — no travel to Mequon required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes. Medicare enrolled per CMS records.

Frequently Asked Questions

Common questions about Melissa M Grube

NPI records show Dr. Grube as active with telehealth listed in Mequon, WI. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (262) 243-9600.

Verified across 6 federal data sources

Sourced from CMS NPPES · OIG LEIE · CMS QPP 2023 · CMS Medicare Part D · CMS Open Payments 2024 · CMS Physician Comparator. See Data Methodology.

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Medical Disclaimer: NPI Telehealth is a provider directory for informational purposes only. This page does not constitute medical advice, diagnosis, or treatment recommendations. Provider data is sourced from the CMS NPPES federal registry and public Medicare datasets. NPI Telehealth does not verify clinical qualifications beyond federal records. Data may not reflect real-time availability — always contact the provider's office directly to confirm details before seeking care.

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