Samuel Fisk Destefano, MD

Epilepsy Psychiatry & Neurology

Samuel Fisk Destefano is an Epilepsy Psychiatry & Neurology specialist based in Littleton, CO with over 13 years of clinical experience. Medicare-enrolled per CMS records and offers virtual telehealth visits.

(303) 730-4400Littleton, CO
Telehealth Available
NPI Active per CMS — Q2 2026|Medicare Enrolled|Order & Refer

Samuel Fisk Destefano, MD has been part of the Littleton medical community since 2013 in group practice. With 13+ years of experience, he has been practicing in the Littleton area. CMS Medicare data shows his patients commonly have hypertension, high cholesterol, and arthritis. CMS MIPS quality score: 97.58/100 (2023).

At a glance

  • Federal MIPS score higher than 50% of MIPS-scored doctors in Colorado
  • Virtual visits available — no app or travel required
1 of 11 Psychiatry & Neurology providers in COSee all Psychiatry & Neurology in Littleton13+ years experienceNPI since 2013

Older · 171dNPPES updated 2025-12-03 · verify NPI on CMS · Verify license at Colorado Medical Board

Contact & Location

Practice Location

7780 S Broadway Ste 350, Littleton, CO 80122-2641

Fax: (303) 730-4401
CMS Clinical Data

How Does This Doctor Compare?

Based on Medicare data, this doctor has an average quality score compared to other doctors in Colorado.

MIPS Score

2023

97.58/100

Colorado avg: 87.4 · US avg: 83.6

Higher than most doctors nationally(+14 pts)

Average range among MIPS-scored doctors in Colorado

How the government rates this doctor's Medicare care quality. Scores above 75 are considered good.

Generic Rx

↑ Higher = better

76.2%

Colorado avg: 81.7 · US avg: 82.8

Lower than most doctors nationally(-6.6 pts)

How often this doctor prescribes affordable generic drugs instead of expensive brand-name ones.

Medicare Patients

79

Unique beneficiaries

Standard volume

Prescription Recipients

73

Patients prescribed

Prescriptions Written

446

Total claims

Total Medicare drug cost: $205k

Percentile rankings compared against 1,617 reporting peers in Colorado.

Data Note: Sourced from CMS Medicare Provider Utilization & Payment Data. Percentile rankings compare this provider against all peers with reported data in the same state. Updated annually to reflect the latest federal reporting cycle.

Patient Condition Panel

What This Doctor Treats Most

Based on Medicare claims data — here's what patients commonly see this doctor for

Based on Medicare data, this doctor primarily manages Hypertension, High Cholesterol, and Arthritis.

Hypertension
Lower than avg (-3%)67%

High blood pressure — a leading risk factor for heart disease and stroke

US avg: 70.2%

↓ Fewer patients than average (-3%) — less common here

High Cholesterol
Lower than avg (-4%)66%

Elevated cholesterol or triglycerides that increase heart disease risk

US avg: 70.4%

↓ Fewer patients than average (-4%) — less common here

Arthritis
49%

Joint inflammation causing pain, swelling, and stiffness

US avg: 49.3%
Mood Disorders
49%

Conditions affecting emotional state, including depression and bipolar disorder

Depression
Higher than avg (+9%)41%

A mood disorder causing persistent sadness and loss of interest in activities

US avg: 31.8%

↑ More patients than average (+9%) — a focus area for this doctor

Anxiety Disorders
Higher than avg (+4%)38%

Excessive worry or fear that interferes with daily life

US avg: 34.1%

↑ More patients than average (+4%) — a focus area for this doctor

Chronic Kidney Disease
Higher than avg (+5%)35%

Gradual loss of kidney function over time, often linked to diabetes or hypertension

US avg: 29.6%

↑ More patients than average (+5%) — a focus area for this doctor

Diabetes
34%

A condition where the body cannot properly regulate blood sugar levels

US avg: 34.5%
GeneralBehavioralNational avg

Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.

Industry Payment Transparency

$393 received from industry

8 transactions reported in 2024 ·Low tier

View on CMS Open Payments →

Payments include consulting fees, speaking honoraria, food & beverage, travel, research support, and ownership interests from drug and medical device manufacturers. Disclosure is required by the federal Physician Payments Sunshine Act. These payments do not necessarily indicate conflicts of interest. National median: $338 across 136 000 tracked providers.

Tiers — Low: under $500 · Moderate: $500-5 000 · High: $5 000-25 000 · Very High: $25 000+. Source: CMS Open Payments 2024, attributed to Samuel Fisk Destefano's NPI.

Patient Reviews

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Background & Specialty

Education, training, and specialty classification from CMS NPPES and Medicare records.

Career Journey
  1. Board certified · Dec 2, 2025

    Self-reported via NPPES

  2. 13 years in practice

    Established

Psychiatry & NeurologyAllopathic & Osteopathic Physicians

Epilepsy is a subspecialty of neurology focused on the diagnosis and treatment of patients with epilepsy, including new-onset, medically refractory epilepsy, psychogenic nonepileptic seizures, and epilepsy in special populations (the elderly, women, patients with co-morbidities). Epilepsy is a multidisciplinary field that provides comprehensive care of the patient.<br/>

Taxonomy: 2084E0001X

Practice Footprint

Primary hospital affiliation: Critical Access Hospitals

CMS Certification Number: 391316

View hospital on Medicare Care Compare

Virtual Psychiatry & Neurology Care With Samuel Fisk Destefano

NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.

Schedule a virtual visit with Samuel Fisk Destefano for blood pressure monitoring, cholesterol management, arthritis follow-ups — no travel to Littleton required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes. Medicare enrolled per CMS records.

Frequently Asked Questions

Common questions about Samuel Fisk Destefano

Dr. Destefano is listed as active in the NPI registry with telehealth listed in Littleton, CO. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (303) 730-4400.

Verified across 6 federal data sources

Sourced from CMS NPPES · OIG LEIE · CMS QPP 2023 · CMS Medicare Part D · CMS Open Payments 2024 · CMS Physician Comparator. See Data Methodology.

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Medical Disclaimer: NPI Telehealth is a provider directory for informational purposes only. This page does not constitute medical advice, diagnosis, or treatment recommendations. Provider data is sourced from the CMS NPPES federal registry and public Medicare datasets. NPI Telehealth does not verify clinical qualifications beyond federal records. Data may not reflect real-time availability — always contact the provider's office directly to confirm details before seeking care.

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