William E Karnes, MD
Gastroenterology Internal Medicine
William E Karnes is a Gastroenterology Internal Medicine specialist based in Orange, CA with over 44 years of clinical experience. Medicare-enrolled per CMS records and offers virtual telehealth visits.
Also practices: GASTROENTEROLOGY
William E Karnes, MD has been part of the Orange medical community since 2006 in independent practice. A University of Minnesota Medical School graduate since 1982, he brings 44+ years of experience. He regularly sees Medicare patients with high cholesterol, hypertension, and arthritis (per CMS claims data). CMS MIPS quality score: 100/100 (2023).
At a glance
- Federal MIPS score higher than 93% of MIPS-scored doctors in California
- Virtual visits available — no app or travel required
Older · 4276dNPPES updated 2014-09-08 · verify NPI on CMS · Verify license at Medical Board of California
Contact & Location
Practice Location
101 the City Dr S Bldg 22c, Orange, CA 92868-3201
How Does This Doctor Compare?
Based on Medicare data, this doctor scores better than 93% of doctors in California on federal quality measures.
MIPS Score
2023100/100
California avg: 78.6 · US avg: 83.6
✓ Higher than most doctors nationally(+16.4 pts)
Top 7% of MIPS-scored doctors in CaliforniaHow the government rates this doctor's Medicare care quality. Scores above 75 are considered good.
Medicare Patients
623
Unique beneficiaries
High volumePrescription Recipients
541
Patients prescribed
Prescriptions Written
1,329
Total claims
Total Medicare drug cost: $278k
Percentile rankings compared against 9,360 reporting peers in California.
Data Note: Sourced from CMS Medicare Provider Utilization & Payment Data. Percentile rankings compare this provider against all peers with reported data in the same state. Updated annually to reflect the latest federal reporting cycle.
What This Doctor Treats Most
Based on Medicare claims data — here's what patients commonly see this doctor for
Based on Medicare data, this doctor primarily manages High Cholesterol, Hypertension, and Arthritis.
Elevated cholesterol or triglycerides that increase heart disease risk
US avg: 70.4%↑ More patients than average (+5%) — a focus area for this doctor
High blood pressure — a leading risk factor for heart disease and stroke
US avg: 70.2%↑ More patients than average (+2%) — a focus area for this doctor
Joint inflammation causing pain, swelling, and stiffness
US avg: 49.3%↑ More patients than average (+6%) — a focus area for this doctor
A condition where the body cannot properly regulate blood sugar levels
US avg: 34.5%↓ Fewer patients than average (-2%) — less common here
Excessive worry or fear that interferes with daily life
US avg: 34.1%↓ Fewer patients than average (-3%) — less common here
Reduced blood flow to the heart muscle, commonly known as coronary artery disease
US avg: 31.7%↓ Fewer patients than average (-2%) — less common here
Conditions affecting emotional state, including depression and bipolar disorder
A mood disorder causing persistent sadness and loss of interest in activities
US avg: 31.8%↓ Fewer patients than average (-6%) — less common here
Percentage of this provider's Medicare patients diagnosed with each condition. Source: CMS Utilization Data.
$518 received from industry
4 transactions reported in 2018 ·Moderate tier
Payments include consulting fees, speaking honoraria, food & beverage, travel, research support, and ownership interests from drug and medical device manufacturers. Disclosure is required by the federal Physician Payments Sunshine Act. These payments do not necessarily indicate conflicts of interest. National median: $338 across 136 000 tracked providers.
Tiers — Low: under $500 · Moderate: $500-5 000 · High: $5 000-25 000 · Very High: $25 000+. Source: CMS Open Payments 2018, attributed to William E Karnes's NPI.
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Background & Specialty
Education, training, and specialty classification from CMS NPPES and Medicare records.
Graduated medical school · 1982
University of Minnesota Medical School
44 years in practice
Senior practitioner
Gastroenterologists diagnose and treat digestive system disorders including GERD, irritable bowel syndrome (IBS), inflammatory bowel disease (Crohn's, ulcerative colitis), liver disease, pancreatitis, and colon polyps. They perform endoscopies and colonoscopies.
Taxonomy: 207RG0100X
Education & Training
University of Minnesota Medical School (Class of 1982)
Primary hospital affiliation: Psychiatric
CMS Certification Number: 194098
View hospital on Medicare Care CompareVirtual Internal Medicine Care With William E Karnes
NPPES records indicate this provider offers telehealth services. Contact the office to confirm availability and scheduling.
Schedule a virtual visit with William E Karnes for cholesterol management, blood pressure monitoring, arthritis follow-ups — no travel to Orange required. The office sends a secure video link before your appointment. Most visits take 15–30 minutes. Medicare enrolled per CMS records.
Frequently Asked Questions
Common questions about William E Karnes
NPI records show Dr. Karnes as active with telehealth listed in Orange, CA. NPI status alone doesn't confirm open availability — call the office to confirm. Phone: (888) 717-4463.
Sourced from CMS NPPES · OIG LEIE · CMS QPP 2023 · CMS Medicare Part D · CMS Open Payments 2018 · CMS Physician Comparator. See Data Methodology.
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Contact William E Karnes
Practice Location
101 the City Dr S Bldg 22c, Orange, CA 92868-3201
Mailing Address
101 the City Dr S Bldg 22c, Orange, CA 92868-3201
This is a provider directory. Contact the office directly to schedule appointments.
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